A volumetric magnetic resonance imaging study in migraine

Abstract Background Although migraine phenotype has been widely described, the explanation of pathophysiology still a gap that might be partly bridged by neuroimaging investigations. The aim study is to assess volumetric brain changes in migraineurs compared with controls, and episodic comparison chronic type. Structural (with without aura) were assessed an automated segmentation method (Free Surfer). T1-weighted MRIs 25 (14 diagnosed as type 11 migraine) headache-free controls evaluated processed. Results Migraine patients had significant reduction volume total brain, grey matter, stem, cerebellum, basal ganglia, thalamus, hippocampus amygdala control subjects. Patients cerebellum frontal lobe thickness those migraine. Conclusion Migraineurs showed mainly areas related central processing pain specific for (such stem) when healthy controls. Chronic involved pain, cognition multisensory integration versus migraine, which adds insight into progressive disorder may have long-term impacts on regards structure function.